Regressive Changes of Senile Brain

Regressive changes in leprosy under promin therapy.

During the past four years continuous intensive treatment with promin has been carried out in a considerable number of patients at the National Leprosarium, as reported by Faget . and others.l These patients have been receiving daily intravenous doses, usually 5.0 grams, with rest intervals of one week for each three of treatment, in some cases for more than four years. It has been the continue...

Senile macular changes in the black African.

One thousand black African and 380 white Caucasian patients over the age of 50 were examined for evidence of age-related macular changes, namely, drusen, pigment epithelial atrophy, and disciform macular degeneration. Drusen and pigment epithelial changes were found to occur twice as commonly in Caucasians as in Africans; there was a much greater difference in the prevalence of disciform macula...

Alzheimer and vascular brain disease: Senile dementia

Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases. He described Senile dementia, a highly heterogeneous condition, and was able not only to distinguish it from syphilitic brain disease, but also to discriminate two clinicopathological subtypes, that may be labeled a "arte...

THE SENILE BRAIN: A Clinical Study

Regressive Changes in the Superficial Layer of Human Articular Cartilage.

By studying changes in the knee joint, Bennett, Waine, and Bauer (1942) were able to trace the development of osteo-arthritis. They showed that the condition initially affects the articular cartilage, a conclusion subsequently supported by Collins (1949). Osteo-arthritic fibrillation is the hallmark of the cartilage lesion. The fibrillated cartilage becomes soft and moist in texture. Chemical a...